Abstract
Interventions to reduce Staphylococcus aureus in the management of eczema.
Highlights
Staphylococcus aureus (S. aureus) can cause secondary infection in eczema, and may promote inflammation in eczema that does not look infected
Topical steroid/ antibiotic combinations may be associated with possible small improvements in good or excellent signs/symptoms compared with topical steroid alone
Eczema treatments intended to reduce S. aureus on the skin include antibiotics, treatments put on the skin, and antibacterial soaps/baths
Summary
Staphylococcus aureus (S. aureus) can cause secondary infection in eczema, and may promote inflammation in eczema that does not look infected. There is no standard intervention to reduce S. aureus burden in eczema It is unclear whether antimicrobial treatments help eczema or promote bacterial resistance. This is an update of a 2008 Cochrane Review. Eczema often occurs in families with atopic diseases including asthma, allergic rhinitis/hay fever (and food allergy), and atopic eczema. These diseases share a common pathogenesis (mechanism of disease), and are frequently present together in the same individual and family. Various terms are used for eczema; despite these synonyms, we will refer to the condition as just 'eczema' throughout the rest of this review This is in agreement with the 'Revised nomenclature for allergy for global use' (Johansson 2004) and similar to other Cochrane Reviews evaluating eczema therapies (Van Zuuren 2017)
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