Abstract

BackgroundMany systematic reviews have evaluated the effectiveness of interventions to prevent, delay, or decrease frailty symptoms, but no effort has been made to identify, map, and synthesize the findings from reviews across the full spectrum of interventions. Our objectives are to (1) synthesize findings from all existing systematic reviews evaluating interventions for preventing, delaying the onset, or decreasing the burden of frailty symptoms; (2) examine different conceptualizations of frailty that have been used in the development and implementation of interventions; and (3) inform policy by convening a stakeholder dialogue with Canadian health-system leaders.Methods/designWe will conduct an overview of systematic reviews to identify and synthesize all of the systematic reviews addressing interventions to preventing, delaying the onset, or decreasing the burden of frailty symptoms. To identify relevant systematic reviews, we will conduct database searches for published and grey literature as well as contact key experts and search reference lists of included reviews. Two reviewers will independently review all search results for inclusion and then conceptually map, extract key findings (including the conceptualization/definition of frailty used) and assess the methodological quality of all included reviews. We will then synthesize the findings by producing a ‘gap map’ (i.e. mapping reviews in a matrix according to the interventions and outcomes assessed), and narratively synthesize the key messages across reviews related to type of interventions.DiscussionFollowing the completion of the synthesis, we will use the findings to develop an evidence brief that mobilizes the best available evidence about the problem related to preventing, delaying the onset, or decreasing the burden of frailty symptoms in older adults, policy and programmatic options to address the problem and implementation considerations. The evidence brief will then be used as the input into a stakeholder dialogue, which will engage 18–22 Canadian health-system leaders (including policymakers, health providers, researchers, and other stakeholders) in ‘off-the-record’ deliberations to inform future actions and policymaking.Systematic review registrationPROSPERO CRD42015022082Electronic supplementary materialThe online version of this article (doi:10.1186/s13643-015-0110-7) contains supplementary material, which is available to authorized users.

Highlights

  • Many systematic reviews have evaluated the effectiveness of interventions to prevent, delay, or decrease frailty symptoms, but no effort has been made to identify, map, and synthesize the findings from reviews across the full spectrum of interventions

  • The evidence brief will be used as the input into a stakeholder dialogue, which will engage 18–22 Canadian health-system leaders in ‘off-the-record’ deliberations to inform future actions and policymaking

  • In general frailty refers to ‘older adults or aged individuals who are lacking in general strength and are unusually susceptible to disease or to other infirmity’ [1]

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Summary

Introduction

Many systematic reviews have evaluated the effectiveness of interventions to prevent, delay, or decrease frailty symptoms, but no effort has been made to identify, map, and synthesize the findings from reviews across the full spectrum of interventions. As a result of population ageing, adverse consequences of frailty, and large social costs and burden for families and caregivers, there is a need to identify effective interventions to prevent or delay the onset as well as decrease the burden of frailty symptoms among older adults. Aiming such efforts at both pre-frail and frail older adults represents an opportunity for preventing or delaying the onset of frailty for those most at risk, improving the effectiveness of prevention and the delivery of care, and improving the health and quality of life for individuals with complex health needs

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