Abstract
In the recent times studies relating the association of Oral and Systemic diseases has gained immense importance because the high occurrence of oral diseases is an extremely common source of infection. Periodontitis is ranked as the sixth most prevalent disease affecting humans affecting 740 million people worldwide. Periodontitis and cardiovascular disease have a complex etiology and genetics and share some common risk factors (i.e., smoking, age, diabetes, etc. The aim of this review is to look at the link between these two diseases. PD is a potential risk factor that may initiate the development, maturation, and instability of atheroma in the arteries. Two mechanisms were proposed to explain such association, either periodontal pathogens directly invade bloodstream or indirectly by increasing systemic level of inflammatory mediators. Interestingly, According to the current literature, it is concluded that there is a strong relationship between these chronic disorders. Improvement in the condition of one disease positively impact the condition of the other one emphasizing the association between these two diseases.
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