Abstract

1H NMR spectroscopy revealed that AM-1/Amanita composite systems are characterized by the significantly higher water binding energy than the starting materials, which can be used to create drug composites with increased retention time of biologically active substances that are a part of the fungus Amanita muscaria. It is in vestigated that the amount of weakly associated water is an order of magnitude smaller and is observed only at high temperatures (T > 270 K), whereas, in the chloroform medium, the number of weakly associated forms of water increases, and it is registered in the whole temperature range. It was found that, at temperatures T > 273 K in hydrophobic-hydrophilic systems AM-1/Amanita, the existence of a metastable solid state of water is possible.

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