Abstract
Seven carbomer 934 lots exhibiting no appreciable differences in IR spectra, density or carboxylic acid group content were found to differ significantly as regards the rheological characteristics of their aqueous dispersions. These differences are attributed to differences in mean molecular weight, and explain significant differences between the two most dissimilar lots as regards the dissolution profiles of theophylline and hydrochlorothiazide tablets in which they were used as matrices.
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