Abstract
Background and aimsMultiple emulsions have excellent encapsulating potential and this investigation has been aimed to encapsulate two different plant extracts as functional cosmetic agents in the W/O/W multiple emulsions and the resultant system’s long term stability has been determined in the presence of a thickener, hydroxypropyl methylcellulose (HPMC).MethodsMultiple W/O/W emulsions have been generated using cetyl dimethicone copolyol as lipophilic emulsifier and a blend of polyoxyethylene (20) cetyl ether and cetomacrogol 1000® as hydrophilic emulsifiers. The generated multiple emulsions have been characterized with conductivity, pH, microscopic analysis, phase separation and rheology for a period of 30 days. Moreover, long term shelf-storage stability has been tested to understand the shelf-life by keeping the generated multiple emulsion formulations at 25 ± 10°C and at 40 ± 10% relative humidity for a period of 12 months.ResultsIt has been observed that the hydrophilic emulsifiers and HPMC have considerably improved the stability of multiple emulsions for the followed period of 12 months at different storage conditions. These multiple emulsions have shown improved entrapment efficiencies concluded on the release rate of conductometric tracer entrapped in the inner aqueous phase of the multiple emulsions.ConclusionMultiple emulsions have been found to be stable for a longer period of time with promising characteristics. Hence, stable multiple emulsions loaded with green tea and lotus extracts could be explored for their cosmetic benefits.
Highlights
In these days the consumers worldwide are looking for personal care products, in specific the cosmetic products that assure multiple benefits
The current study investigates the development of a stable cosmetic multiple emulsion loaded with green tea and lotus extracts which serve as functional cosmetic agents
The green tea in our study has shown a stronger antioxidant activity than lotus, irrespective of the extraction yield of green tea that has been found to be much lower than lotus extract
Summary
In these days the consumers worldwide are looking for personal care products, in specific the cosmetic products that assure multiple benefits They expect the latest advancements of technology to be incorporated into these innovative product formulations. Due to the unique structure and properties, these multiple emulsions are interesting carrier systems for various drug delivery approaches [8] especially for the controlled release of actives [9]. These multiple emulsions have been generated using cavitation technique [10,11,12,13]. Multiple emulsions have excellent encapsulating potential and this investigation has been aimed to encapsulate two different plant extracts as functional cosmetic agents in the W/O/W multiple emulsions and the resultant system’s long term stability has been determined in the presence of a thickener, hydroxypropyl methylcellulose (HPMC)
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