Abstract
Simultaneous measurements of motor activity in the lower esophageal sphincter (LES) and the stomach were recorded continuously for several weeks by means of chronically implanted force transducers in five conscious dogs. We found that the LES contracted precisely in association with the gastric body during the interdigestive state. During this time a series of simultaneous contractions arose in the LES, gastric body, and antrum; these contractions lasted for 25±2.1 min and then stopped abruptly. This active period was followed by a long period of motor quiescence (78±3.6 min). These cyclic recurring episodes of contractions in the LES and the stomach continued until the next meal. Our findings suggest that the interdigestive contractions in the LES act as the orad seal of the stomach during the interdigestive contractions and thus prevent the reflux of the gastric contents into the esophagus during this period.
Published Version
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