Abstract
The program FRODO is implemented on the Vector General 3400 (with DEC, VAX, or PDP-11 computers), MMS-X, Evans & Sutherland PS 2 (PDP-11), MPS (VAX or PDP-11), and PS300. The advantages of building a model with FRODO rather than in a Richards box including speed, accuracy, control and volume. FRODO has extensive model-making features to produce coordinates from a given sequence which have standard bond lengths and angles and preferred torsion angles. FRODO is designed as a tool for the practicing protein crystallographer. However, some of its features make it of more use: the flexible coordinate data set and the absence of any connectivity dictionary mean that any sort of molecular fragment can be displayed, the fragment rotation/translation with neighbor calculations can be used to dock substrates into active sites and this has recently been enhanced to include local energy minimization, and the edit features in the SAM option allow one to change residue types and delete or insert new residues.
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call