Abstract
This in vitro study analyses the biochemical interaction between saliva and three types of dental composite resins (a direct resin, an indirect resin and a dual-cure resin used for cementation of indirect dental restorations). The resin samples were obtained following a specific protocol and in line with the producers� recommendations; the resin samples were incubated with saliva samples collected from 19 healthy volunteers. The obtained results showed that the tested composite resins did not produce significant changes in oxidative stress parameters that were analysed (albumin, uric acid, GGT / gamma glutamyl transferase, OXSR-1 / oxidative stress responsive kinase 1) and do not influence the inflammatory salivary status reflected by the levels of IL-6 - an inflammatory marker.
Highlights
This in vitro study analyses the biochemical interaction between saliva and three types of dental composite resins
The specialised literature is rich in topics related to composite resins for dental use, addressing, especially, topics such as: the mechanical behaviour of composite resins; biocompatibility; correlations between the physico-chemical properties of composite resins and their biocompatibility; the elements released by the composite resins immediately post-polymerisation and at different time intervals; conversion rate; specific techniques to ensure the photopolymerisation depth; the adhesion shrinkage of composite resins; improvement of composite resins with certain substances that confer antiseptic abilities; the cytotoxic effect of dental composite resins on pulp cells or on gingival fibroblasts etc
We have analysed the biochemical interaction between saliva and three different dental composite resins: a resin used for obtaining direct dental restorations, a resin used for obtaining indirect dental restorations, as well as a composite resin used for cementation of indirect dental restorations
Summary
MIHAELA PANTEA1, DIANA ANDREEA IGHIGEANU2, ALEXANDRA TOTAN3*, MARIA GREABU3, DANIELA MIRICESCU3, MARINA MELESCANU IMRE4*, COSMIN TOTAN5, TUDOR CLAUDIU SPINU1, ALEXANDRU PETRE1, ANGELICA BENCZE6, STEFAN MILICESCU7, ANA MARIA CRISTINA TANCU4 1 University of Medicine and Pharmacy Carol Davila, Faculty of Dental Medicine, Department of Fixed Prosthodontics and Occlusion, 17-23 Calea Plevnei, 010221, Bucharest, Romania 2 University of Medicine and Pharmacy Carol Davila, Faculty of Dental Medicine, 17-23 Calea Plevnei, 010221, Bucharest, Romania 3 University of Medicine and Pharmacy Carol Davila, Faculty of Dental Medicine, Department of Biochemistry, 8 Eroilor Sanitari Blvd, 050474, Bucharest, Romania 4 University of Medicine and Pharmacy Carol Davila, Faculty of Dental Medicine, Department of Complete Denture, 17-23 Calea Plevnei, 010221, Bucharest, Romania 5 University of Medicine and Pharmacy Carol Davila, Faculty of Dental Medicine, Department of Oral and Maxillofacial Surgery, 17- 23 Calea Plevnei, 010221, Bucharest, Romania 6 University of Medicine and Pharmacy Carol Davila, Faculty of Dental Medicine, Department of Orthodontics, 17- 23 Calea Plevnei, 010221, Bucharest, Romania 7 University of Medicine and Pharmacy Carol Davila, Faculty of Dental Medicine, Department of Prosthodontics, 17- 23 Calea Plevnei, 010221, Bucharest, Romania This in vitro study analyses the biochemical interaction between saliva and three types of dental composite resins (a direct resin, an indirect resin and a dual-cure resin used for cementation of indirect dental restorations). Certain salivary parameters are evaluated – albumin, uric acid, GGT / gamma glutamyl transferase, OXSR-1 / oxidative stress responsive kinase 1 - for the purpose of analysing the antioxidant activity of these composite resins, as well as the levels of IL-6
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