Interaction problems of drugs and food in older patients. Short Review

Abstract

The interaction between drugs and food in the body of older patients is an important therapeutic problem. As a result of this interaction, both the assimilation of food by the patient's body and the effectiveness and safety of drug therapy can change. Older patients may develop several complications and adverse reactions that change the underlying disease course against the background of age-related metabolic and functional disorders that change both the drugs' pharmacokinetics and pharmacodynamics and the metabolism of food substances. Considering the compatibility mechanisms of medicinal substances with certain food products, compliance with appropriate food regimes is a necessary condition for the effectiveness and drug therapy safety for older patients. __________________________________________________________________________________________ Keywords: older patients; drugs; food; therapeutic problem; pharmacokinetics; pharmacodynamics