Abstract
In this work we describe the interaction of the responses of neuronal networks to pairs of electrical stimuli. For this we use networks of dissociated cortical neurons cultured on planar microelectrode arrays. We compare the response to pairs of stimuli with the response to a stimulus in isolation. To evaluate the influence of both stimuli we introduce a normalization of the root-mean square of the response. Furthermore we consider the response to a pair of stimuli as the linear superposition of the two constituents. The two methods combined show that the neuronal network strongly suppresses the second stimulus. At the same time we find a possible window of integration in which two stimuli from separate locations in the network can interact to form a new response.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
