Abstract

Purpose To investigate the interaction between corneal, internal, and total wavefront aberrations (WAs) and their influential factors during orthokeratology (OK) treatment in Chinese adolescents. Methods Thirty teenagers (n = 30 eyes) were enrolled in the study; spherical equivalent refraction (SE), corneal curvature radius (CCR), central corneal thickness (CCT), WAs, and the difference in limbal transverse diameter and OK lens diameter (ΔLLD) were detected before and after one-month OK treatment. Every component of WAs was measured simultaneously by iTrace aberrometer. The influential factors of OK-induced WAs were analyzed. Results SE and CCT decreased while CCR increased significantly (P < 0.01). Higher-order aberrations (HOAs), Spherical aberrations (SAs), and coma increased significantly (P < 0.01). Corneal horizontal coma (Z31-C) and corneal spherical aberrations (Z40-C) increased (P < 0.01). The HOAs, coma, SAs, Z31-C, Z31-T, Z40-C, and Z40-T were positively correlated with SE and CCR (P < 0.01). Z3−1-C showed negative correlations with (ΔLLD) and positive correlations with SE (P < 0.05). Conclusions The increase in OK-induced HOAs is mainly attributed to Z31 and Z40 of cornea. Z3−1 in the internal component showed a compensative effect on the corneal vertical coma. The degree of myopic correction and increase in CCR may be the essential influential factors of the increase in Z31 and Z40. The appropriate size of the OK lens may be helpful to decrease OK-induced vertical coma.

Highlights

  • Myopia has become a significant public health problem worldwide, especially in some Asian countries, where it presents a massive socioeconomic burden on society [1]

  • The corneal aberrations were obtained with the Vista attachment of the wavefront aberrometer, and aberrations in the internal optics were calculated by subtracting the aberrations of the cornea from those of the entire eye measured by the ray-tracing aberrometer using a built-in program [19]

  • The central corneal thickness (CCT) was decreased from 548.17 ± 35.05 μm to 532.00 ± 35.72 μm (P < 0.01, paired t-test)

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Summary

Introduction

Myopia has become a significant public health problem worldwide, especially in some Asian countries, where it presents a massive socioeconomic burden on society [1]. It was reported that HOAs was correlative with age [16], cause in young eyes, corneal aberrations could be compensated by internal aberrations. Such a compensatory effect could be found in patients after corneal laser refractive surgery [17]. The OK-induced HOAs usually present an increase in coma-like aberrations and a positive shift in spherical aberrations (SAs) [10, 12], but the interaction between corneal and internal aberrations in children and adolescents who are wearing OK lenses is still unknown

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