One-year effect of wearing orthokeratology lenses on the visual quality of juvenile myopia: a retrospective study.

Yewei Yin,Dan Wen,Xiaobo Xia,Weitao Song,Yang Zhao,Xiaoying Wu,Xia Zhou,Kelly Young,Mengyang Jiang,Shengfa Hu,Yao Chen

doi:10.7717/peerj.6998

Abstract

ObjectiveTo study the one-year effect of wearing orthokeratology (OK) lenses on the visual quality of juvenile myopia.MethodsThe right eyes of 36 juvenile myopias were retrospectively studied in this work. Q-value, e-value, corneal curvature, strehl ratio (SR), modulation transfer function (MTF) and wavefront aberration (WA) were compared before and at 1, 3 and 12 months after wearing OK lenses. The SR, MTF and WA of cornea, internal optic and ocular were analyzed separately. The spherical and cylinder diopter, vision acuity, compensating factor (CF) and compensative rate (CF%) were compared before and at 12 months after wearing OK lenses.Results(1) The vision of LogMAR increased and the corneal curvature decreased significantly after wearing OK lenses. There was no significant difference for the e-value before and after wearing OK lenses. The Q-value increased at 1 month but decreased at 3 and 12 months remarkably. (2) The ocular and internal optic SR and MTF increased significantly at 1 month and then remained stable. The MTF in different spacial frequencies increased after wearing OK lenses. There was no significant difference for the corneal SR before and after wearing OK lenses, and the corneal MTF decreased significantly after wearing OK lenses. (3) For the ocular, the total higher order aberration (HOA), spherical, coma and trefoil aberrations increased, and the total aberration, total lower order aberration (LOA) and defocus aberration decreased obviously except astigmatism. The corneal aberrations increased significantly after wearing OK lenses except astigmatism. For the internal optic, the total aberration, total LOA and defocus aberration decreased, and the total HOA, coma and trefoil aberration increased significantly except the astigmatism and spherical aberrations. (4) The CF and CF% of total aberration, total LOA, total HOA and coma aberrations increased, and those of astigmatism and spherical decreased at 12 months.ConclusionsOrthokeratology is effective in correcting the refractive error and improving the vision quality of juvenile myopia over the one-year follow-up period.

Highlights

Orthokeratology (OK) is a non-invasive technology for refractive correction (Cho et al, 2008) and has been widely applied to treat young myopic patients since the 1990s (Dave & Ruston, 1998)
The one-way repeated measurement analysis of variance was applied to analyze the differences of the corneal curvature, Q-value, e-value, strehl ratio (SR), modulation transfer function (MTF) and wavefront aberration (WA) before and at 1, 3 and 12 months after wearing OK lenses when the data followed the law of normal distribution; if not, Friedman test was used. p < 0.05 was considered statistically significant for the visual acuity, diopter and compensating factor (CF), and the adjusted alpha i.e., alpha/no. of test, was applied for the analysis with repeated measurement
The descriptive statistics of the myopic teenagers before and after wearing OK lenses were summarized in Table 1. 19 females and 17 males aged of (10.8 ± 2.2) years old were enrolled in the study

Summary

Introduction

Orthokeratology (OK) is a non-invasive technology for refractive correction (Cho et al, 2008) and has been widely applied to treat young myopic patients since the 1990s (Dave & Ruston, 1998). The corneal aberrations increased significantly after wearing OK lenses except astigmatism.

Results

Conclusion