Intensity of protein synthesis in skeletal muscle fibers when the androgen balance is disturbed

Abstract

Injection of testoterone propionate into castrated male Wistar rats (0.4 mg daily for 7 days) stimulates the incorporation of methionine-2-H3 into nuclei of the fibers of the gastrocnemius laterialis muscle 3 h after injection of the labeled compound into the animals, and then stimulates its incorporation into the cytoplasm until 16 h. At these same times the incorporation of the label into nuclei of the soleus muscle fibers is inhibited.