Intensity Modulated Radiotherapy in Giant Cell Bone Tumor and Aneurysmal Bone Cyst-Imaging and Pathohistological Differential Diagnosis and Achieved Long-Term Healing Results after Radiation Therapy

Abstract

We present two clinical cases in young patients with the rare pathohistological diagnosis of giant cell bone tumor (GCT) and aneurysmal bone cyst (ABC). Against this background, we discuss the rare indications for intensity modulated radiotherapy (IMRT). We focus on the imaging and pathohistological differences, as well as in terms of biological development in these two osteoclastic tumors with a high risk of recurrence after the inability to perform radical operations due to their localization.