Abstract
ObjectiveThis study aimed to evaluate the power of integrative weaning index (IWI) in predicting the success rate of spontaneous breathing trial (SBT) in the mechanically ventilated patients.BackgroundThe use of weaning predictive indicators can avoid early extubation and wrongful prolonged mechanical ventilation. This study aimed to evaluate the effectiveness of IWI in predicting the success rate of SBT in patients under mechanical ventilation.Patients and methodsIn this prospective study, 120 patients undergoing mechanical ventilation for more than 48 h were enrolled. Before weaning initiation, the IWI was calculated and based on the defined cutoff point (≥44), the success rate of SBT was predicted. If they were in the normal range besides the patient's tolerance, the test was considered a success. The result was then compared with the IWI and further analyzed.ResultsThe SBT was successful in 96 (80%) and unsuccessful in 24 (20%) cases. The difference between the true patient outcome after SBT, and the IWI prediction was 0.833 according to the Kappa agreement coefficient (P < 0.001). Moreover, regarding the predictive power, IWI had high sensitivity (96.87%), specificity (95.83%), positive and negative predictive values (98.8 and 88.5%), and accuracy (96.7%).ConclusionThe IWI as a more objective indicator has acceptable accuracy and power for predicting the SBT result.
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