Integration of lipase catalysis and product separation in supercritical carbon dioxide

Abstract

Summary In this work the effect of different flow rates on the selective extraction of the ethyl esters synthesised in a lipase catalysed alcoholysis reaction of cod liver oil was studied. Further, we investigated the phase behaviour of the reaction medium. The results showed that a fast flow rate both results in a higher extraction rate of ethyl esters and shifts the equilibrium of the reaction towards further synthesis. In addition, this work has established that the reaction medium comprises of two phases.