Abstract
Sugar transporters belong to a ubiquitous family of membrane proteins that transport sugarmolecules across the membrane cycling cycles through 4 conformational states following a rocker-switch mechanism. To transport sugar molecules, the large conformational changes required are induced by substrate binding. The current view of the mechanism has evolved with the deposition of new structures in the PDB database, currently numbering 17. However, the present view is based on comparing structures of different transporters, between which factors such as membrane environment, substrate specificity, and kinetics vary significantly.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
