Abstract
This study proposes a surface-enhanced Raman scattering (SERS) chip integrated with a liquid core waveguide. Due to the total reflection, the chip suppresses the leaky waveguide mode and enables a long propagation distance for SERS signal collection. A 10 nM rhodamine 6G Raman signal was obtained using a QE65000 portable microspectrometer at a low excitation power intensity of 14.5 W/cm2. The proposed SERS chip was also used to detect the SERS spectrum of a silkworm DNA solution, the structural information of which was clearly shown. In addition, due to the lower excitation power density, damage to the structure of the biomolecule was avoided.
Published Version
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