Abstract
Integrated Physiological and Biochemical Assessments for the Prediction of Growth of Abdominal Aortic Aneurysms in Humans.
Highlights
To the Editor: Abdominal aortic aneurysms (AAAs) are pathological dilatations of the abdominal aorta to larger than 30 mm in diameter
Methods for the prediction of AAA growth are regarded as an important gap in existing literature according to the Vascular Surgery Societal Guidelines.[1,2]
The Oxford Abdominal Aortic Aneurysm (OxAAA) Study has previously reported the importance of flow-mediated dilatation of the brachial artery (FMD, a physiological marker of systemic endothelial function) as a novel biomarker of AAA progression.[4]
Summary
To the Editor: Abdominal aortic aneurysms (AAAs) are pathological dilatations of the abdominal aorta to larger than 30 mm in diameter. The Oxford Abdominal Aortic Aneurysm (OxAAA) Study has previously reported the importance of flow-mediated dilatation of the brachial artery (FMD, a physiological marker of systemic endothelial function) as a novel biomarker of AAA progression.[4] We showed that using 2 variables (FMD and AAA diameter) measured at baseline, it Is feasible to predict the growth rate of individual patients at future 12 and 24 months with modest accuracy.[5]
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