Abstract

Photoplethysmography (PPG) is a non-invasive technique that employs near infrared light to estimate periodic oscillations in blood volume within arteries caused by the pulse pressure wave. Importantly, combined Electrocardiography (ECG) and PPG can be employed to quantify arterial stiffness. The capabilities of a home-made multi-channel PPG-ECG device (7 PPG probes, 4 ECG derivations) to evaluate arterial ageing were assessed. The high numerosity of channels allowed to estimate arterial stiffness at multiple body locations, without supra-systolic cuff occlusion, providing a fast and accurate examination of cardiovascular status and potentially allowing large scale clinical screening of cardiovascular risk.

Highlights

  • Cardiovascular insult is the main cause of death in developed countries [1]

  • All subjects were Caucasian, and they reported with no history of cardiovascular or psychiatric disease; they did not consume medications or drinks before the experiment, that was performed in agreement with the Helsinki Declaration and approved by the Ethical Committee of the local university

  • The PPG-ECG system was developed at STMicroelectronics (Figure 1a) and it was composed by

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Summary

Introduction

Cardiovascular insult is the main cause of death in developed countries [1]. Cardiovascular risk assessment is challenging, because acute vascular events, such as stroke and infarction, often occur without a clear underlying cardiovascular pathology [1]. Cardiovascular status can be assessed through markers indicative of asymptomatic atherosclerosis based on the characteristics of the pulse pressure wave propagating through the arterial tree. Photoplethysmography (PPG) [2] is a noninvasive optical technique that exploits light in the near infrared (NIR) spectral range to measure blood volume oscillations induced by the pulse wave propagation from the heart within the peripheral arteries. The measured light intensity is sensitive to changes in volume of the arteries caused by the pulse pressure wave

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