Abstract
A cavity-enhanced spectrometer is developed for detection of exhaled nitric oxide in human breath. A thermoelectrically cooled, pulsed, quantum cascade laser, coupled to a high-finesse cavity, is used for trace-gas measurements. The trace-gas analyzer operates at 5.2 microns and utilizes integrated cavity output spectroscopy. Effective optical path lengths of 1.5 km are achieved in a 50-cm-length cell with a sample volume of 60 mL. The instrument is also capable of simultaneously measuringCO2 concentration in exhaled breath. Measurements were performed on human breath samples as well as simulated breath samples. Here we report a detection limit of ≤ 1 ppbv in 4 s for NO in human breath samples.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
