Abstract
Current therapies for postherpetic neuralgia (PHN) frequently provide incomplete pain relief and their use is often limited by side effects. NGX-4010 is a high-concentration capsaicin dermal patch (capsaicin, 8%) being evaluated as a treatment for PHN. We conducted an integrated analysis using data from 4 controlled PHN studies with 597 patients receiving a single 60-minute treatment with NGX-4010 and 530 control (low-concentration capsaicin patch [0.04% w/w]) patients. Throughout a 12-week controlled study period, patients recorded their “average pain for the past 24 hours” daily using an 11-point Numeric Pain Rating Scale (NPRS).
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