Intact Mass Analysis of Complex Therapeutic Proteins under Native Conditions

Abstract

Genetic Engineering & Biotechnology NewsVol. 37, No. 15 Bioprocessing PerspectivesIntact Mass Analysis of Complex Therapeutic Proteins under Native ConditionsTo Characterize the Inherent Microheterogeneity of mAbs, One Must Consider the Surrounding mAb EnvironmentSimon Cubbon, Aaron Bailey, and Kai SchefflerSimon CubbonSimon Cubbon, Ph.D., is vertical marketing manager, Thermo Fisher Scientific, U.K.; Aaron O. Bailey, Ph.D., is mass spectrometry specialist, Thermo Fisher Scientific, U.S.; and Kai Scheffler, Ph.D., is biopharma support expert, Thermo Fisher Scientific, Germany. Website: www.thermofisher.com.Search for more papers by this author, Aaron BaileySimon Cubbon, Ph.D., is vertical marketing manager, Thermo Fisher Scientific, U.K.; Aaron O. Bailey, Ph.D., is mass spectrometry specialist, Thermo Fisher Scientific, U.S.; and Kai Scheffler, Ph.D., is biopharma support expert, Thermo Fisher Scientific, Germany. Website: www.thermofisher.com.Search for more papers by this author, and Kai SchefflerSimon Cubbon, Ph.D., is vertical marketing manager, Thermo Fisher Scientific, U.K.; Aaron O. Bailey, Ph.D., is mass spectrometry specialist, Thermo Fisher Scientific, U.S.; and Kai Scheffler, Ph.D., is biopharma support expert, Thermo Fisher Scientific, Germany. Website: www.thermofisher.com.Search for more papers by this authorPublished Online:28 Aug 2017https://doi.org/10.1089/gen.37.15.12AboutSectionsView articleView Full TextPDF/EPUB Permissions & CitationsPermissionsDownload CitationsTrack CitationsAdd to favorites Back To Publication ShareShare onFacebookTwitterLinked InRedditEmail View articleFiguresReferencesRelatedDetails Volume 37Issue 15Sep 2017 InformationCopyright © GEN PublishingTo cite this article:Simon Cubbon, Aaron Bailey, and Kai Scheffler.Intact Mass Analysis of Complex Therapeutic Proteins under Native Conditions.Genetic Engineering & Biotechnology News.Sep 2017.26-27.http://doi.org/10.1089/gen.37.15.12Published in Volume: 37 Issue 15: August 28, 2017PDF download