Abstract

Recombinant human interferon α1b(IFN-α1b)is the first internationally unique novel genetic engineering medicine in China.As a major interferon subtype with natural antiviral activity, IFN-α1b has high safety and broad-spectrum antiviral effect, so it has broad application prospects in the treatment of viral diseases.Chinese pediatric doctors have taken the lead globally in conducting clinical research of IFN-α1b in the treatment of respiratory syncytial virus(RSV)pneumonia、bronchiolitis、hand-foot-mouth disease, herpetic angina、viral diarrhea, etc.A series of clinical guidance and expert consensus have been published which are in line with China′s national conditions.This article summarizes the innovative research of IFN-α1b and proposes common issues and potential application in pediatric clinical applications. Key words: Interferon-α1b; Children; Virus; Innovation

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