Abstract
The presented material considers the possibility of combining sparingly soluble polysaccharides with plant polysaccharides to increase the absorption of drugs with low bioavailability, as biologically active substances they can serve as a targeted carrier for the delivery of diagnostic and therapeutic agents, as well as enzymes, nucleic acids, vitamins or hormones, to certain cells, in particular hepatocytes (parenchymal liver cells). A method for preparing a composition of arabinogalactan and chitosan succinate is described, examples of its practical use in medicine, veterinary medicine and animal husbandry are given.
Highlights
The presented material considers the possibility of combining sparingly soluble polysaccharides with plant polysaccharides to increase the absorption of drugs with low bioavailability, as biologically active substances they can serve as a targeted carrier for the delivery of diagnostic and therapeutic agents, as well as enzymes, nucleic acids, vitamins or hormones, to certain cells, in particular hepatocytes
It was shown [3,4,5,6] that hypertension from western larch can serve as a targeted carrier for the delivery of diagnostic and therapeutic agents, as well as enzymes, nucleic acids, vitamins or hormones, to certain cells, in particular hepatocytes
The structural feature of AG macromolecules can contribute to the formation of strong intermolecular complexes of active substances, the molecules of which are most likely to be bound by intermolecular hydrogen bonds in the space formed by the side chains
Summary
The presented material considers the possibility of combining sparingly soluble polysaccharides with plant polysaccharides to increase the absorption of drugs with low bioavailability, as biologically active substances they can serve as a targeted carrier for the delivery of diagnostic and therapeutic agents, as well as enzymes, nucleic acids, vitamins or hormones, to certain cells, in particular hepatocytes (parenchymal liver cells). The structural feature of AG macromolecules can contribute to the formation of strong intermolecular complexes of active substances, the molecules of which are most likely to be bound by intermolecular hydrogen bonds in the space formed by the side chains. The presence of high electron density hydroxyl groups with lone electron pairs along the molecule leads to the formation of hydrogen bonds with other biopolymer compounds; first of all, strong complexes with lipids and proteins are formed in which chitosan acts as a nucleus [6].
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
