Abstract

The presented material considers the possibility of combining sparingly soluble polysaccharides with plant polysaccharides to increase the absorption of drugs with low bioavailability, as biologically active substances they can serve as a targeted carrier for the delivery of diagnostic and therapeutic agents, as well as enzymes, nucleic acids, vitamins or hormones, to certain cells, in particular hepatocytes (parenchymal liver cells). A method for preparing a composition of arabinogalactan and chitosan succinate is described, examples of its practical use in medicine, veterinary medicine and animal husbandry are given.

Highlights

  • The therapeutic effect of ultrasonic electrical stimulation is better than that of traditional acupuncture and massage for recent pain after minimally invasive interventional therapy with disc degenerative diseases (DDD), it is worthy to popularize in clinical treatment

  • Spinal degenerative radicular pain is a kind of disease characterized by pain in the innervated area of spinal cord

  • Spinal degenerative radicular pain is a kind of disease characterized by pain in the innervated area of spinal cord caused by the invasion of nerve roots

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Summary

Methods

The patients in two groups were treated with ultrasonic stimulation and conventional conservative therapy respectively after minimally invasive interventional therapy. In the electric stimulation group, the corresponding spinal nerve innervation area was treated with ultrasonic electric stimulation. The patients in conservative treatment group were treated with conventional acupuncture and massage once a day for 20 minutes for 3 consecutive days to assess the pain, and the patients in the conservative treatment group were scheduled for outpatient follow-up and assessment one week and one month later. 3 days, 7 days and 1 month after treatment, the pain degree of patients was evaluated by pain number rating scale (NRS). The evaluation of curative effect was carried out after the treatment one month by NRS weighting method. Total effective rate = (cureative+ excellent + effective) / total number of patients. The measurement data was described by mean ± standard deviation (M±SD.) difference between groups was compared by independent t test or one-way ANOVA (SNK method was used for the pairwise comparison), and the level of statistical significance was taken as P < 0.05

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