Innate immunity of pregnant women with a history of chronical endometritis

Abstract

This was a prospective study in a group of 130 pregnant women. The main group (group I) included 100 pregnant women with a history of chronical endometritis, the control group (group II) – 30 women of physiological pregnancy and with no history of obstetrical and gynecological disorders. Pregnant women of group I were divided into two subgroups. The subgroup IA includes 75 patiens which pregnancy ended in time and the condition of newborns was fine. The subgroup IB was included 30 patiens which pregnancy ended are unsuccessful (premature birth, neonatal infection, perinatal death). As a result of research was noted activation mechanisms of congenital immunity of women with a history of chronical endometritis and which pregnancy ended are unsuccessful. An increase of the pro-inflammatory potential of blood serum and cervical slime at pregnant women with a history of chronical endometritis may be linked with a chronic intrauterine infection and can be used in the prognosis of adverse perinatal outcomes.