Inhibitory Potentials of Kappaphycus Alvarezii on Bacteria Isolated from Clinical Samples

Abstract

Kappaphycus alvarezii is one of the high stress tolerant sea weed with good biopotentials. This was collected, processed, extracted and subjected to antibacterial activity against MDR UTI isolates. All the isolates were identified using standard biochemicals and other textual procedures along with 16S rRNA sequencing. Antibacterial activity was assessed by disc diffusion method and followed standard textual procedures to assess MIC, MBC, Percentage inhibition, IC50 and LC50. Six different test organisms were used for studying antibacterial activity. Antibacterial activity of all extracts on different extracts were varied from 7.2±0.6mm zone of inhibition. Concentration required to inhibits the growth of the UTI causing test organisms found to varied from 383.3±57.7µg/ml to 1033.0±76.3 µg/ml. extracts inhibited the growth of bacteria especially Staphylococcus aureus var haemolyticus was up to 98.2%. antibacterial substances like flavonoids and phenolic compounds could be responsible for this kind of activity.