Abstract
The in vitro migration of spleen cells from BALB/c mice infected with Rauscher leukemia virus (RLV) was markedly inhibited 10 days after RLV inoculation. Mixtures of infected and uninfected spleen cells used in the ratio of 1:4 in an effector-cell/indicator-cell system showed that viable RLV-infected spleen cells could inhibit the migration of uninfected spleen cells in a manner indistinguishable from that mediated by sensitized spleen cell reacting to specific antigen.
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