Abstract
Hematopoietic stem cell inhibition factor (SCIF), liberated by lymphocytes treated with antilymphocytic globulin, causes inhibition of migration of the spleen cells of intact mice. The degree of inhibition of migration corresponds to the colony-inhibiting activity of the SCIF. Macrophage migration inhibition factor (MMIF) obtained in the H-2 system has a stimulating effect on exocolonization in mice on treatment of a bone-marrow graft in vitro. The colony-stimulating activity of MMIF corresponds to its inhibitory effect on migration of spleen cells. Incubation of bone marrow cells with MMIF for 30 min is more effective than incubation for 2 h. It is suggested that SCIF and MMIF are not identical with one another.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
