Abstract
In recent studies on ion transport in mitochondria (1,2) oligomycin has been shown to inhibit calcium transport under conditions in which ATP, rather then electron transport, provides energy for the process. Active transport of calcium is totally dependent upon the presence of ATP in isolated granules composed of skeletal muscle sarcoplasmic reticulum, and an effect of oligomycin was sought on this system in the belief that some of the basic features of the calcium transport process might be common to both systems.
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