Abstract
The transport of GABA through the mierodissected plasma membrane Deiters' neurone reflects the physiological event of postsynaptic uptake of GABA by its uptake carrier. Sodium valproate at concentrations ⩾2.4mM was able to decrease markedly (57%) such a transport. This effect, which reduces the efficiency of the GABA postsynaptic inactivation process, might be a mechanism for the potentiation by valproate of the synaptic action of GABA.
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