Influences of γ-ray irradiation on physico-chemical, structural, X-ray diffraction, thermal and antimicrobial activity of some γ-irradiated N′,N′′′-((Z)-ethane-1,2-diylidine)bis(2-aminobenzohydrazide) metal complexes

Abstract

A series of Co(II), Ni(II), Cu(II), Th(IV) and UO2(II) complexes have been synthesized from reaction of nitrogen based ligand (L) i.e. N′,N′′′-((Z)-ethane-1,2-diylidine)bis(2-aminobenzohydrazide)(L) with their salts. Investigation of synthesized metal complexes was achieved by using elemental analyses, magnetic moment, molar conductance, FT-IR, UV/Vis. spectroscopy, thermal techniques and 3D molecular modeling. An octahedral geometry has been suggested for all complexes except for Ni(II) complex (2) which adopted tetrahedral geometry. To through a light on the probability of structure changes with γ-irradiation, the effect of gamma irradiation on powder samples of the complexes [Co(L)Cl2].4H2O (1); [Ni2(L)(OAc)4].5H2O (2) and [Cu(L)Br2].5H2O (3) was investigated after being exposed to high energetic γ-rays at 100 kGy dose (hereafter referred to as (1A,2A,3A, respectively). Spectral, thermal, magnetic susceptibility, molar conductance and powder X-ray diffraction patterns (XRD) were performed before and after irradiation. In addition, the in vitro antimicrobial activity of the complexes against Staphylococcus aureus as Gram-positive strain, Escherichia coli as Gram-negative strain and antifungal Candida albicans was performed for both unirradiated and irradiated samples. The obtained results showed that the irradiated complexes were affected, but not greatly by the applied γ-irradiation dose.