Influence of the probiotic preparation immunofloor on the immune status of broiler chickens

Abstract

In conditions of intensification of the livestock industry, to combat infectious pathology, antimicrobial drugs are most often, and in some cases haphazardly, used, which accumulate in raw materials and food products and contribute to environmental pollution. Antibiotics have a detrimental and pathogenic effect on the normal microflora of the gastrointestinal tract of animals and poultry. Against this background, dysbiosis is observed, leading to metabolic disorders, decreased digestibility of essential feed nutrients, and the development of immunological deficiency. One of the leading areas of agricultural science and practice is developing and introducing drugs and feed additives that are an alternative to antibiotics into livestock farming. Probiotics have a unique role in solving this problem. Probiotic preparations ’ therapeutic and prophylactic properties are based on maintaining normal flora at a physiologically necessary level, reducing diarrhea in animals, and improving digestion processes. Probiotics have thefunctions of improving metabolic processes, immunostimulating activity, adaptogenic effects, increasing all types of productivity offarm animals and poultry, and improving the quality of livestock products. Introducing probiotic preparations into poultry and livestockfarming requiresfurther study of their biological properties and immunostimulating activity. The influence of the probiotic drug Immunoflor on the state of natural resistance factors in poultry was studied. Four groups of day-old broiler chickens of the Arbor Acres cross were formed: a control group and three experimental groups. In addition to the main diet, the birds of the experimental groups received Immunoflor in amounts of 0.5, 0.7, and 1.0 kg/t of feed. It was established that the inclusion of aprobiotic drug in the diet of broilers contributed to the strengthening of humoral factors of natural resistance due to an increase in the lysozyme and bactericidal activity of blood serum by 10.5 - 17.2 and 8.5 - 12.1% by the end of cultivation. The phagocytic properties of chicken blood leukocytes have also improved. Under the influence of Immunoflor, an increase in the mass of immunocompetent organs was observed in 42-day-old broiler chickens. The maximum indicators of poultry population safety were established in the experimental groups.