Abstract
AbstractThe optimal liquid requirement for wet granulation can be investigated by recording the power consumption of the mixer during liquid addition. In this work it was tried to use this technique on a small laboratory scale (one kg or less) for lactose wet granulation with water. The validity of the power consumption method could be confirmed by granule size analysis. Different factors were studied: kind of mixer, powder quantity, mixer speed, liquid addition speed, granulator screen size, mixing time.
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