Abstract
The constant interaction between bacteria in the gastrointestinal tract, intestinal epithelial cells and immune system cells is a continuous interaction that is central to maintaining immune homeostasis.
 "Analtsim-Si" is a montmorillonite rock of Volodymyretsky field. Probiotic "Sporo-lex" is a mixture of probiotic cultures of Bacillus licheniformis VK-25 and Bacillus subtilis MK-3 on a natural standardized sorbent – montmorillonite rock of Volodymyretsky field. The subjects were laying hens of 130 days of age, Lohmann Brown cross (n = 30). The bird of the first group got compound feed with 2% of "Analtsim-Si", the bird of the second group got compound feed with 2% of the probiotic "Sporo-lex". The third group – was a control group and received the usual food.
 Prior to the start of the study, as well as on days 7, 14 and 28, the bird was weighed, blood and feces were collected for the study. On the 27th day of the experiment, a pathological examination of birds from all groups was performed to study the patency of the gastrointestinal tract.
 The effect of experimental veterinary drugs "Sporo-lex" and "Analtsim-Si" on the microflora of the gastrointestinal tract of poultry was established. The drug "Sporo-lex" has a more pronounced effect, which is manifested in the suppression of bacteria of the Escherichia coli group due to the antagonistic action of strains of Bacillus licheniformis VK-25 and Bacillus subtilis MK-3, which are part of the drugs.
 The average growth of turkeys during the use of the probiotic "Sporo-lex" was studied. As a result of the conducted researches it was established that the bird of the experimental group at the end of the experiment had 470 grams more body weight compared to the control. During the autopsy of birds from both groups, no significant signs of pathology of organs and systems were detected.
 In the future, it is necessary to study the effect of drugs "Sporo-lex" and "Analcym-Si" on the dynamics of changes in the immunological parameters of birds.
Highlights
До початку досліджень, а також на 7, 14 та 28 добу птицю зважували, відбирали кров та фекалії на дослідження
The constant interaction between bacteria in the gastrointestinal tract, intestinal epithelial cells and immune system cells is a continuous interaction that is central to maintaining immune homeostasis
2. Властивість препарату «Анальцим-Si» зменшувати концентрацію бактерій групи кишкової палички (БГКП) в фекаліях тварин та птиці, пояснюється сорбційними властивостями, а також властивістю до підвищення бактерицидної та лізоцимної активності сироватки крові
Summary
А також на 7, 14 та 28 добу птицю зважували, відбирали кров та фекалії на дослідження. Встановлено вплив дослідних ветеринарних препаратів «Споро-лекс» та «АнальцимSi» на мікрофлору шлунково-кишкового тракту птиці. При цьому препарат «Споро-лекс» має більш виражений вплив, що проявляється у пригніченні бактерій групи кишкової палички за рахунок антагоністичної дії штамів Bacillus licheniformis VK-25 та Bacillus subtilis MK-3, які входять до складу препаратів. Мікрофлору шлунково-кишкового тракту птиці при застосуванні препаратів на основі монтморилонітової породи (сорбент мікотоксинів) та спороутворюючих пробіотичних мікроорганізмів, вивчено не достатньо.
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