Abstract
The development of photoprotective lipsticks containing natural bioactive compounds is a relevant current strategy to increase sun protection factor (SPF) value and lower the concentration of chemical UV filters, known for promoting sensitivity reactions. Twelve photoprotective lipsticks were developed by Design of Experiment (DOE) and characterized to verify the influence of Shea butter (Butyrospermum parkii), titanium dioxide (TiO2 ), and ethylhexyl methoxycinnamate (EHM) on physical parameters and in vitro photoprotective efficacy. The influence of Shea butter, TiO2, and EHM was evaluated by several parameters, such as melting point, colorimetry, thermal analysis by DSC, texture analysis, and sunscreen activity estimated in vitro. The construction of prediction models was possible for the following responses: maximum force by the cantilever test at 25 and 45°C; maximum distance by hardness test at 25°C; slope value at 25 and 45°C by the cantilever test; and UVA/UVB ratio and in vitro SPF. TiO2 and EHM contributed to changes on the in vitro SPF value; however, unexpectedly, Shea butter had no influence on this efficacy parameter. The assay allowed us to observe the influence of the variables in the analysis and to develop a response prediction model for some of the parameters assessed.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
