Abstract
Objective. Study of the effect of Rheosorbilact on the rheological properties of blood in patients with acute peritonitis.
 Materials and methods. 62 patients with acute peritonitis at the age from 20 to 87 years were examined. The patients were divided into two groups depending on the inclusion of Rheosorbilact solution in the infusion therapy program. The first group (control) included 30 patients with the infusion therapy program consisted of conventional crystalloid and colloidal infusions. The second (main) group included 32 patients with the treatment of Rheosorbilact infusion therapy program at an average dose of 5.7-6.6 ml/kg (400 ml per day). The rheological properties of blood were studied by determining the relative blood viscosity with a VK-4 viscometer, hematocrit, fibrinogen and ESR according to generally accepted methods.
 Results. In patients with acute peritonitis, when Rheosorbilact (main group) is included in the infusion therapy program, there is a significant improvement in the rheological properties of blood compared with the results of the control group who received crystalloids and colloids. After treatment in patients of the control group, the indicators of the rheological properties of blood were characterized by a decrease in hematocrit – by 16.5 %, blood viscosity – by 11.6 %, fibrinogen content – by 15.2 %, ESR – by 18.2 % compared to the initial data. In patients of the main group who received Rheosorbilact in the infusion therapy program, the rheological properties of the blood significantly improved and amounted to 24.0 % in comparison with the initial data on hematocrit, 18.7 % in blood viscosity, 21.0 % in fibrinogen, and 23.4 % in ESR.
 Conclusions. In patients with acute peritonitis, a significant violation of the rheological properties of blood is observed. The inclusion of Rheosorbilact in the infusion therapy program contributes to the correction of impaired blood.
Highlights
The patients were divided into two groups depending on the inclusion of Rheosorbilact solution in the infusion therapy program
The rheological properties of blood were studied by determining the relative blood viscosity with a VK-4 viscometer, hematocrit, fibrinogen and ESR according to generally accepted methods
In patients with acute peritonitis, when Rheosorbilact is included in the infusion therapy program, there is a significant improvement in the rheological properties of blood compared with the results of the control group who received crystalloids and colloids
Summary
Влияние Реосорбилакта на реологические свойства крови у больных острым перитонитом Хамидов Д.Б., Косимов З.К., Бобоев Б.Р, Халифаев У.Р., Холназаров Ш.Э. Изучение влияния Реосорбилакта на реологические свойства крови у больных острым перитонитом. У больных острым перитонитом при включении в программу инфузионной терапии Реосорбилакта (основная группа) наблюдалось значительное улучшение реологических свойств крови по сравнению с результатами контрольной группы, получавшей кристаллоиды и коллоиды. После лечения у больных контрольной группы показатели реологических свойств крови характеризовались снижением гематокрита – на 16,5 %, вязкости крови – на 11,6 %, содержания фибриногена – на 15,2 %, СОЭ – на 18,2 % по сравнению с исходными данными. У больных основной группы реологические свойства крови значительно улучшились и составили по сравнению с исходными данными по гематокриту – 24,0 %, по вязкости крови – 18,7 %, по фибриногену – 21,0 % и по СОЭ – 23,4 %.
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