ИЗМЕНЕНИЕ РЕОЛОГИЧЕСКИХ СВОЙСТВ КРОВИ У БОЛЬНЫХ С РИНОСИНУСИТАМИ ПОСЛЕ КОРОНАВИРУСНОЙ ИНФЕКЦИИ

Abstract

Introduction. The study of the pathogenesis of purulent-inflammatory diseases of the nose and paranasal sinuses is impossible without a comprehensive analysis of various factors of homeostasis and, above all, the state of microcirculation, which largely depends on the rheological properties of blood Under the law common to all forms of fluid movement, as the viscosity of the medium increases, the speed of movement decreases, and the energy costs for its movement increase. Consequently, the deterioration of the rheological properties of blood and microcirculation are directly related. Violation of microcirculation always significantly affects the development of pathological processes. The aim of the study rheological properties of blood in patients with rhinosinusitis after coronavirus infection. Materials and methods. The studying the rheological properties of blood in 55 patients with rhinosinusitis after coronavirus infection are presented. The following main indicators were determined in patients: blood viscosity, erythrocyte aggregation coefficient, degree of deformability of erythrocytes, average volume of one erythrocyte, hematocrit, fibrinogen, morphological properties of erythrocytes. Results and discussion. In all examined patients with rhinosinusitis after coronavirus infection, the rheological properties of blood are sharply impaired. The severity of violations of the rheological properties of blood depended not only on the type of disease, but on its severity and the degree of intoxication of the body. A change in blood viscosity was detected in all examined patients. Blood viscosity indices increased sharply in proportion to the severity and prevalence of the inflammatory process and the severity of destructive changes in the affected organs. Conclusion. The analysis of the conducted studies shows that one of the main manifestations of a violation of the rheological properties of blood in rhinosinusitis after coronavirus infection is intravascular aggregation of erythrocytes, as well as a violation of the ability of erythrocytes to reversible deformation.