Abstract
It is shown that in experiments on narcotic male rats of the Wistar line using laser Doppler flometry (LDF) under conditions of induced (ligature) experimental periodontitis (EP), indicators of blood microcirculation in the gum mucosa in the lower incisors is reduced compared with intact periodontium. When using traditional drug therapy (TDT) in the conditions of EP in the selected localization, observed a significant promotion in blood microcirculation after a 12-day period of treatment. However, on the 74th day of the study, it decreases. The use of TDT in combination with gel, containing cluster silver in the form of micelle monomers and cluster monomers of the AgK+ type and superoxide dismutase, and a new injectable form, which is a recombinant human superoxide dismutase, under EP conditions in the selected field of study both after applying the pharmacological composition for twelve days, and on the 74th day of the experiment caused an increase in microcirculation to the original values.
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