Abstract

The effect of different concentrations of deltamethrin (0.5, 1.0, 2.0 and 4.0 ppm) on the carp erythrocyte plasma membrane was examined. Carp erythrocyte plasma membrane was exposed to deltamethrin for 48 and 96 hrs. Results showed that the deltamethrin pol­lutants significantly (P'$;0.0l) led to a decrease of phosphatidylethanolamine (PE), phosphoglyceride (PG) and phosphatidic acids (PA), with higher concentrations of deltamethrin leading to elimination of phosphatidic acids and cardiolipin (CL). Deltamethrin also brought about a marked difference in the fatty acid patterns of the phospholipids in the erythrocyte plasma membrane. Higher concentrations lead to increased levels of saturated fatty acids, primarily palm­itic (16:0) and stearic acid (18:0) as well as polyunsaturated fatty acids (PUFA), especially arachidonic acid (20:4 n-6). Of monounsaturated fatty acids (MUFA), palmitoleic acid (16:1 n-7) and oleic acid (18:1 n-9) did not increase significantly. At the same time the level of omega-3 polyunsaturated fatty acids [eicosapentaenoic (EPA, 20:5 n-3) and docosahexaenoic acid (DHA, 22:6 n-3)] significantly (P:-:;0.01) decreased, making the membrane more rigid and less permeable.

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