Abstract
Exposure to ouabain of isolated toad epithelia such as urinary bladder or abdominal skin, was regularly followed by decreases of short-circuit current and, to a lesser extent, of electrical potential difference; the inhibition was a function of ouabain concentration, and it proved reversible upon withdrawal of the glycoside from the incubation solution. Frog skin behaved similarly, with the notable exception that it was found to be much more sensitive to the glycoside.
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