Influence of mother's treatment for syphilis on the incidence of congenital syphilis in newborn babies

Abstract

Objective To explore the influence of mother's treatment for syphilis on the incidence of congenital syphilis in newborn babies.Methods 40 cases of neonatal congenital syphilis,according to mother different treatment methods,were divided into regular treatment group (20 cases),mother without regular treatment group (10 cases),mother with no treatment group (10 cases).The incidence of neonatal congenital syphilis was compare.Results The neonatal congenital syphilis could affect multiple systems,manifested as skin damage,pathological jaundice,hepatosplenomegaly,edema,anemia,thrombocy to penia,bone injury,cerebrospinal fluid abnormalities et al.The incidence rate of neonatal congenital syphilis in regular treatment group was 10％,which was significantly lower than normal treatment 40％ and untreatment 50％ (x2 =11.2,P ＜ 0.05 ; x2 =20.4,P ＜ 0.01).The neonatal congenital syphilis incidence rate was not statistically significant between the informal group and untreatment group (x2 =0.68,P ＞ 0.05) ;30 cases were cured (75 ％),improved in 7 cases (17％) ;3 cases died (7 ％).Conclusion The prevention and treatment of syphilis infection in mothers are the key point to prevent neonatal congenital syphilis. Key words: Syphilis, congenital; Infant, newborn