Influence of micronuitrients on cadmium toxicity

Abstract

There is growing evidence that micronutrient intake can lead to the development of poisoning and carcinogenesis caused by various chemicals. The article considers the question of the influence of the status of micronutrients on the toxicity of cadmium. After analyzing the literature data from both Russian and foreign databases (Scopus, Web of Science, RSCI), it was found that this topic on the effect of trace elements on the toxicity of heavy metals is relevant for scientists of various profiles.Cadmium interacts with the metabolism of four metals necessary for a balanced diet: Zn, Fe, Ca, and Cu. As can be seen from the analysis of literature sources, one of the important aspects of cadmium metabolism is its interaction with the sulfhydryl protein metallothionein.Like heavy metals, micronutrient availability in soil is affected by a number of factors. First, the availability of trace elements is directly or indirectly determined by the physicochemical and biological properties of the soil, such as pH, redox potential, soil organic matter content, complexing ligands, and underground biotic interactions. Based on the literature data, and analyzing the data obtained, it can be concluded that this issue remains relevant to this day. There have been few studies specifically designed to investigate the effect of micronutrient status on toxicity from non-essential metal exposure.Thus, many factors other than diet can greatly influence the metabolism of toxicants in the body, and require further research.