Influence of Live High Train High on Physiological Training Adaptations and Athletic Performance in Trained Runners: An Observational Cohort Case Study

Abstract

Introduction: Live high-train high (LHTH) is suggested to improve performance, especially maximal aerobic capacity through the hypoxic adaptation responses. The present study aims to determine the impact of LHTH protocol on cardio-respiratory variables, lactate response, iron profile indices, and lung function capacities to the performance enhancement of middle-long distance (MLD) runners. Methods: Seven MLD runners were trained LHTH for six weeks at 8000ft altitude. Cardio-respiratory variables (V̇O2max, VO2/HR, VEmax, HR response), lactate response, iron profile indices (Hb, iron, UIBC, TIBC, transferrin, EPO, ferritin), and lung function parameters (FVC, FEV1, FEV1/FVC, PEF, and VC) were measured via standard protocols. Result: Hemoglobin (Hb, 7.8%), iron concentration (36.7%), and TIBC (8.2%) were found to be significantly increased after LHTH. On the other hand, V̇O2max (6.4%) and PEF (10.7%) were found to be significantly (p < 0.05) increased after camp. But HRrest (1.8%), HRrec (5min and 10min with 2.3% and 4.7% respectively), and lactate peak (7.9%) significantly decreased after LHTH condition. Discussion: All participating athletes improved performances after LHTH (overall group improved by 1.7%, individual increase up to 2.6%). Specific training load with hypoxic stress at high altitude induces peripheral chemoreceptor activation and stimulates sympathetic drive to initiate adaptive cascade leading to V̇O2max improvement (improved group mean 6.4%, individually up to 16.7%) which might be supported by enhanced erythropoiesis, iron metabolism, Hb concentrations, peak expiratory flow, glycolytic enzyme activity, enhanced oxidative capacity, improved resting and recovery HR response and peak lactate tolerance.