Abstract
Narkates, Annie J. (Southern Research Institute, Birmingham, Ala.), and Robert F. Pittillo. Influence of inoculum media on sensitivity of Escherichia coli to azaserine. J. Bacteriol. 90:710-714. 1965.-Escherichia coli grown in a simple synthetic medium is more than 100-fold more sensitive to inhibition by azaserine than E. coli grown in complex, undefined organic medium. The work reported here offers two explanations for this observed effect: (i) concentration within the cell from the complex medium of a specific azaserine-reversing metabolite (nicotinic acid), and (ii) stimulation by exogenous metabolite(s) of intracellular synthesis of azaserine-reversing agents.
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
