Abstract
Polylactic acid (PLA) is a very attractive material for applications in the field of regenerative medicine and tissue engineering, as it is a biocompatible and biodegradable synthetic polymer, whose morphological properties can be finely tuned via laser processing. Ultra-short pulse laser treatment is a non-invasive method for optimizing the surface properties of engineered biomatrices. The method offers controlled porosity of the treated biomaterial tailored specifically for implantation needs. In this research, we investigated the interaction of femtosecond laser radiation with PLA stacks while varying the output laser parameters in order to estimate their influence on the morphology of the PLA samples. The induced microstructural features were characterized by thickness measurements and SEM, EDX and FTIR analyses. In order to evaluate the hydrophilicity of the treated surface, water contact angle (WCA), measurements were also performed. Topography modification of the PLA substrates could essentially improve this material’s bioactivity properties, which, after proper optimization of the laser parameters, could make its biomedical applications even more successful.
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