Abstract
Adrenaline potentiates the thrombin-induced aggregation of rabbit blood platelets in platelet-rich citrated plasma in vitro. In rabbits, simultaneous administration of adrenaline and thrombin results in a decrease in platelet count and the appearance of fibrin monomer. The adrenaline-potentiated effect of thrombin is prevented in vitro and in vivo by previous administration of dihydroergotoxine.
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