INFLUENCE OF CYTRIMIN ON LEUKOCYTE FORMULA STRUCTURE OF FISH

Abstract

An obvious trend in domestic and foreign aquaculture in recent years is usage of biologically active substances of various mechanisms of action. It was clearly demonstrated that such biologically active substances as adaptogens, probiotics, vitamins, amino acids have a positive effect on the fish organism, increasing economic parameters of the industry. In particular, usage of "Irkutin" adaptogen in early ontogenesis of fish increased survivability of larvae during transition to exogenous nutrition, survivability of the fry, growth rate, endurance and it also reduced the level of cannibalism and stress. Therefore, the search for new substances with the properties of adaptogens for fish farming is of great importance. There is reason to believe that "cytrimin" can become such new substance. "Cytrimin" is a complex of tris-(2-hydroxyethyl) amine with zinc bis-(2-methylphenoxyacetate) and has the formula: (HOCH2CH2)3N Zn(OOCCH2OC6H4CH3-2)2. A study of the spectrum of physiological activity of "cytrimin" (one of the representatives of protatrans) showed that it protects blood vessels from formation of cholesterol plaques, it is also an antidote to alcohol and can increase performance, claiming to be an adaptogen. So far, "cytrimin" has not been used in fish farming. The aim of the work was to study the effect of "cytrimin" on parameters of blood system, in particular, on the structure of leukocyte formula of the African sharptooth catfish. It was found that there were no significant changes in the content of the total number of leukocytes in the blood of African catfish in case of "cytrimin" application, however, a redistribution of functionally different groups of cells in the leukogram of the African catfish was revealed. This redistribution was expressed in a slight decrease in the proportion of lymphocytes with a significant increase in the proportion of segmented neutrophils and monocytes within the physiological norm.